Nylon-derived film dressings were initially avoided for significantly exuding wounds due to their inadequate absorption capacity and propensity to cause maceration of the wound and the healthy tissues surrounding it. Films were initially occlusive since they were made of nylon derivatives and supported by an adhesive polyethylene frame. These dressings are made of translucent, adherent polyurethane, which permits gaseous exchange from the wound for oxygen, carbon dioxide, and water. The 20th century saw the introduction of modern wound dressings. Antibiotics were developed in the 19th century, marking a significant advance in the antiseptic technique. They used wine or water-boiled wool as a bandage. Hippocrates of ancient Greece practiced the use of wine or vinegar for washing the wounds with honey, oil, and wine as further treatment from 460 to 370 Before Common Era. Before applying a honey or resin bandage, they cleansed the wounds with water or milk. Beginning around 2500 Before Common Era, clay tablets of Mesopotamian origin were used to cure wounds. In 1600 Before Christ, linen strips wrapped in plaster and saturated in oil or grease were used to patch wounds. Wet-to-dry dressings have long been a popular choice for wounds that need to be debrided. A bandage holds the dressing in place, whereas a dressing is intended to be in contact with the wound. It is crucial to properly care for any wound, regardless of how severe it is, which involves applying wound dressing. Honey, animal oils or fat, cobwebs, mud, leaves, sphagnum moss, and animal excrement were a few of these items. Since the beginning of time, a variety of substances have been applied to wounds to halt bleeding, absorb exudates, and speed up healing. In this manuscript, the “three healing gestures” were defined as: washing the wound, applying dressings, and bandaging. According to English literature, the world’s oldest medical document and the first written historical record were both discovered on Sumerian clay. The history of medicine and wound care has been extensively documented. In order to reach the closest attainable tensile strength (80%) of the original structure, the scar mutation continues for a considerable amount of time. Scar tissue’s newly laid down collagen is eliminated by releasing, activating, or inhibiting numerous preteolytic and degradative enzymes, such as matrix metalloproteinase.ī. A number of cytokines and growth factors, such as vascular endothelial growth factor, are crucial.Ī. Epithelialization and neovascularization are present, as well as fibroblast activity and granulation of extracellular matrix components.ī. Recruitment of cells such as keratinocytes, monocytes, and polymorphonuclear leukocytes, which are crucial for the development of wound healing.Ī. Through platelet activation and the release of growth factors, including platelet derived growth factor (PDGF), and pro-inflammatory cytokines, fibrin clot is formed to achieve hemostasis.Ī. Histamine, serotonin with other vasoactive substances is released as a result of blood factor leakage.ī. It also provides a detailed classification of traditional and modern wound dressings.Ī. The objective of the article is to enhance knowledge about characteristics of an ideal wound dressing and guide in finding the correct dressing material. There are a number of wound dressings available in the market. The development of new and effective treatments in wound care still remains an area of intense research. There is a growing concern about the usage of correct materials for wound dressings. Wound tissue never reaches its pre-injured strength and multiple aberrant healing states can result in chronic non-healing wounds. The sequence of events involved in wound healing can be affected by numerous disease processes, resulting in chronic, non-healing wounds that give significant discomfort and distress to the patients while draining the medical fraternity of enormous resources. Wound healing process recruits three different phases: inflammation, proliferation, and maturation. Injury to the skin provides a difficult challenge, as wound healing is a complex and dynamic process.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |